Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407831 | 1.00 | CTSC (0.50) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL21964312 | 1.00 | CTSC (0.50) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL12480861 | 1.00 | CTSC (0.50) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL19388654 | 1.00 | CTSC (0.50) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| Hydrochloric Acid SCHEMBL25201793 | 0.99 | TSHR (0.52) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| Hydrochloric Acid SCHEMBL29820504 | 0.99 | TSHR (0.52) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| Trifluoroacetic Acid SCHEMBL20238954 | 0.94 | CTSC (0.48) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL8607040 | 0.89 | CTSC (0.46) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL6167045 | 0.89 | CTSC (0.46) | CTSCTSHRBACE1ALDH1A1HTR2C | |
| SCHEMBL10062407 | 0.86 | TSHR (0.58) | TSHRBACE1ALDH1A1HTR2CFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-3668863-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036377-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2019-02-21 | — | — | WO | disclosed |