Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.53 |
| ▸ | CHIT1 | Q13231 | 18/20 | 0.52 |
| ▸ | CHIA | Q9BZP6 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901751 | 0.87 | KCNH2 (0.68) | KCNH2CHIT1CHIA | |
| SCHEMBL22903714 | 0.87 | KCNH2 (0.68) | KCNH2CHIT1CHIA | |
| SCHEMBL18577126 | 0.85 | CHIT1 (0.71) | KCNH2CHIT1CHIA | |
| SCHEMBL18577260 | 0.85 | CHIT1 (0.71) | KCNH2CHIT1CHIA | |
| SCHEMBL18609992 | 0.85 | CHIT1 (0.57) | KCNH2CHIT1CHIA | |
| SCHEMBL20628957 | 0.85 | CHIT1 (0.57) | KCNH2CHIT1CHIA | |
| SCHEMBL18607729 | 0.83 | CHIT1 (0.68) | KCNH2CHIT1CHIA | |
| SCHEMBL18609888 | 0.83 | CHIT1 (0.68) | KCNH2CHIT1CHIA | |
| SCHEMBL21565738 | 0.83 | CHIT1 (0.68) | KCNH2CHIT1CHIA | |
| SCHEMBL18577068 | 0.83 | CHIT1 (0.68) | KCNH2CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | Oncoarendi Therapeutics S.A. (PL) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208020-B2 | Substituted amino triazoles useful as human chitinase inhibitors | CHIA, CHIT1, AADAC | KCNH2 3882/4885CHIT1 2/4885CHIA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.