Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.54 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSH | P09668 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20747657 | 0.94 | DAGLA (0.53) | DAGLACSNK1ETYRCTSKCTSL | |
| SCHEMBL20747723 | 0.81 | ALPI (0.49) | DAGLAALPIPKMPTGS1XIAP | |
| SCHEMBL20747654 | 0.80 | CSNK1E (0.52) | DAGLACSNK1ETYRALDH1A1ALPI | |
| SCHEMBL27293262 | 0.80 | DAGLA (0.50) | DAGLACSNK1ETYRCTSKCTSL | |
| SCHEMBL18067508 | 0.79 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7780482 | 0.78 | TYR (0.55) | DAGLACSNK1ETYRALDH1A1ALPI | |
| SCHEMBL21585495 | 0.78 | TYR (0.55) | DAGLACSNK1ETYRALDH1A1ALPI | |
| SCHEMBL17901647 | 0.78 | ALPI (0.47) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL22654085 | 0.78 | TYR (0.55) | DAGLACSNK1ETYRALDH1A1ALPI | |
| SCHEMBL22654084 | 0.78 | TYR (0.55) | DAGLACSNK1ETYRALDH1A1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | DAGLA 4177/4885CSNK1E 2665/4885TYR 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.