Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075380 | 0.92 | HDAC1 (0.68) | HDAC1KCNH2MCHR1HTR2C | |
| SCHEMBL2076495 | 0.88 | HDAC1 (0.75) | HDAC1KCNH2MCHR1HTR2C | |
| SCHEMBL5112809 | 0.88 | HDAC1 (0.68) | HDAC1KCNH2MCHR1HTR2CALDH1A1 | |
| SCHEMBL2077803 | 0.85 | HDAC1 (0.82) | HDAC1KCNH2MCHR1HTR2C | |
| SCHEMBL2074826 | 0.83 | HDAC1 (0.53) | HDAC1KCNH2 | |
| SCHEMBL2076388 | 0.80 | HDAC1 (0.52) | HDAC1KCNH2 | |
| SCHEMBL12772580 | 0.77 | HDAC1 (0.70) | HDAC1KCNH2MCHR1HTR2C | |
| SCHEMBL2077871 | 0.77 | HDAC1 (0.96) | HDAC1KCNH2MCHR1HTR2C | |
| SCHEMBL2074748 | 0.77 | HDAC1 (0.47) | HDAC1KCNH2 | |
| SCHEMBL2076346 | 0.77 | HDAC1 (0.47) | HDAC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | disclosed |