Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074826 | 0.90 | HDAC1 (0.53) | HDAC1KCNH2TRPV1LMNACYP1A2 | |
| SCHEMBL2076242 | 0.89 | HDAC1 (0.48) | HDAC1KCNH2TRPV1LMNACYP1A2 | |
| SCHEMBL5106569 | 0.86 | HDAC1 (0.58) | HDAC1KCNH2TRPV1LMNACYP1A2 | |
| SCHEMBL2075380 | 0.84 | HDAC1 (0.68) | HDAC1KCNH2 | |
| SCHEMBL2077612 | 0.84 | HDAC1 (0.71) | HDAC1KCNH2 | |
| SCHEMBL2074748 | 0.83 | HDAC1 (0.47) | HDAC1KCNH2TRPV1LMNACYP1A2 | |
| SCHEMBL2076495 | 0.82 | HDAC1 (0.75) | HDAC1KCNH2 | |
| SCHEMBL2076346 | 0.82 | HDAC1 (0.47) | HDAC1KCNH2TRPV1LMNACYP1A2 | |
| SCHEMBL2074841 | 0.80 | HDAC1 (0.60) | HDAC1KCNH2 | |
| SCHEMBL5794402 | 0.78 | HDAC1 (0.50) | HDAC1KCNH2TRPV1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | disclosed |