Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 7/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930 | 0.83 | ADORA2A (0.48) | NSD2NSD3HPGDADORA2API4KA | |
| SCHEMBL30670814 | 0.83 | ADORA2A (0.48) | NSD2NSD3HPGDADORA2API4KA | |
| SCHEMBL8093 | 0.80 | NSD2 (0.46) | NSD2NSD3ADORA2API4KAPI4K2B | |
| SCHEMBL30670884 | 0.80 | NSD2 (0.46) | NSD2NSD3ADORA2API4KAPI4K2B | |
| SCHEMBL30694902 | 0.80 | TBK1 (0.38) | PRMT5ABL1SRCMAPTHPGD | |
| SCHEMBL11533 | 0.80 | TBK1 (0.38) | PRMT5ABL1SRCMAPTHPGD | |
| SCHEMBL30013159 | 0.77 | ADORA2A (0.49) | NSD2NSD3HPGDADORA2API4KA | |
| SCHEMBL8903 | 0.77 | ADORA2A (0.49) | NSD2NSD3HPGDADORA2API4KA | |
| SCHEMBL30670834 | 0.77 | NSD2 (0.46) | NSD2NSD3ADORA2API4KAPI4K2B | |
| SCHEMBL8248 | 0.77 | NSD2 (0.46) | NSD2NSD3ADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444242-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2019-02-20 | — | — | EP | disclosed |