Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20748843 | 0.88 | POLB (0.31) | — | |
| SCHEMBL20748874 | 0.82 | PDE4D (0.36) | — | |
| SCHEMBL20748885 | 0.78 | CSNK1E (0.48) | CSNK1DCSNK1E | |
| SCHEMBL21131229 | 0.77 | CSNK1E (0.51) | CSNK1DCSNK1E | |
| SCHEMBL20748882 | 0.76 | CSNK1E (0.46) | CSNK1DCSNK1E | |
| SCHEMBL20748938 | 0.74 | RIPK2 (0.45) | CSNK1DCSNK1E | |
| SCHEMBL20748937 | 0.74 | CSNK1E (0.52) | CSNK1DCSNK1E | |
| SCHEMBL20748866 | 0.74 | CSNK1E (0.55) | CSNK1DCSNK1E | |
| SCHEMBL20748869 | 0.71 | — | — | |
| SCHEMBL20748895 | 0.67 | TLR9 (0.42) | CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068785-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-3068784-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-02-20 | — | — | EP | disclosed |