Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632696 | 0.71 | — | — | |
| SCHEMBL1760799 | 0.69 | PTPN7 (0.56) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL9367475 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17377642 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL29020570 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17965756 | 0.69 | — | — | |
| SCHEMBL21294357 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL11484029 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL17965749 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL19359550 | 0.69 | PTPN7 (0.46) | PTPN7HMGCRKCNH2RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054927-B1 | FORMULATIONS OF (S)-3-(4-((4-(MORPHOLINOMETHYL)BENZYLOXY)-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE | CELGENE CORP (US) | 2019-02-20 | — | — | EP | disclosed |