SCHEMBL1760799

SCHEMBL1760799

CCCCCC#CCCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.56
HMGCR P04035 2/20 0.56
RECQL P46063 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
ALOX12 P18054 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52
MCL1 Q07820 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.50
EPHX2 P34913 2/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290566 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL11175213 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL513302 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL11066113 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL10796010 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL23040316 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL9211891 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL9374800 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL1523678 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E
SCHEMBL11071774 0.96 PTPN7 (0.61) PTPN7HMGCRRECQLTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130860-A1 LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS FLAGSHIP LABS 114, INC. (US) 2026-05-14 US claimed
EP-4687854-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY Flagship Labs 114, Inc. (US) 2026-02-11 EP claimed
WO-2024211865-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY OMEGA THERAPEUTICS, INC. (US) 2024-10-10 WO claimed
US-20240339358-A1 METHOD OF FORMING A METAL LINER FOR INTERCONNECT STRUCTURES APPLIED MATERIALS, INC. (US) 2024-10-10 US claimed
WO-2024211169-A1 METHOD OF FORMING A METAL LINER FOR INTERCONNECT STRUCTURES APPLIED MATERIALS, INC. (US) 2024-10-10 WO claimed
WO-2024073678-A2 PHOSPHOLIPIDS CONTAINING A HETEROCYCLE RING HAVING A TERTIARY AMINE OR AMIDE OMEGA THERAPEUTICS, INC. (US) 2024-04-04 WO claimed
WO-2023225621-A2 LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS OMEGA THERAPEUTICS, INC. (US) 2023-11-23 WO claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
CN-107074886-B Stable photochromic compounds having silicon-or phosphorus-containing heterocycles and process for their production 香港大学 2020-09-15 CN claimed
US-9708528-B2 Robust photochromic compounds with silicon- or phosphorus-containing heterocyclic ring and the production thereof THE UNIVERSITY OF HONG KONG (HK) 2017-07-18 US claimed
US-20150361332-A1 ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (HK) 2015-12-17 US claimed
US-8436118-B2 Synthesis of acylarylenes and hyperbranched poly(aclarylene)s by metal-free cyclotrimerization of alkynes THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2013-05-07 US claimed
CN-102964317-A New preparation method of tetrasubstituted furan compound DALIAN CHEMICAL PHYSICS INST 2013-03-13 CN claimed
EP-2181763-B1 Catalyst and process for alkoxylation SHELL INT RESEARCH (NL) 2012-06-20 EP claimed
US-20100129757-A1 SYNTHESIS OF ACYLARYLENES AND HYPERBRANCHED POLY(ACLARYLENE)S BY METAL-FREE CYCLOTRIMERIZATION OF ALKYNES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-05-27 US claimed
WO-2008151499-A1 SYNTHESIS OF ACYLARYLENES AND HYPERBRANCHED POLY(ACYLARYLENE)S BY METAL-FREE CYCLOTRIMERIZATION OF ALKYNES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2008-12-18 WO claimed
EP-4748965-A2 FORMULATIONS FOR SELECTIVE DEPOSITION Merck Patent GmbH (DE) 2026-05-27 EP disclosed
EP-4743602-A1 FORMULATIONS FOR SELECTIVE DEPOSITION Merck Patent GmbH (DE) 2026-05-20 EP disclosed
US-4061772-A HYPOURICEMIC, URICOSURIC, HYPOLIPIDEMIC HOECHST AKTIENGESELLSCHAFT (DT) 1977-12-06 US disclosed
US-4001431-A DERIVATIVES OF THE 1,2-DIARYLETHYLENE- AND PHARMACEUTICAL COMPOSITIONS THEREOF HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130860-A1 LIPIDS FOR DELIVERY OF THERAPEUTIC AGENTS NSUN3, NSUN2, LDLR PTPN7 2194/4885HMGCR 460/4885RECQL 976/4885
US-20150361332-A1 ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF CRY1, CRY2, P2RY10 PTPN7 1941/4885HMGCR 4665/4885RECQL 789/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK PTPN7 3021/4885HMGCR 4231/4885RECQL 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.