Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418607 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL15540261 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL28364982 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL28885159 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL15540019 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL15538398 | 0.86 | ALDH1A1 (0.46) | TSHRCA1CA2MAPTHTT | |
| SCHEMBL14626064 | 0.83 | TSHR (0.66) | TSHRMAPTHTTALDH1A1CYP1A2 | |
| SCHEMBL14626063 | 0.83 | TSHR (0.66) | TSHRMAPTHTTALDH1A1CYP1A2 | |
| SCHEMBL18169376 | 0.81 | CYP3A4 (0.38) | TSHRMAPTHTTALDH1A1HPGD | |
| SCHEMBL18169378 | 0.81 | CYP3A4 (0.38) | TSHRMAPTHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443959-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2019-02-20 | — | — | EP | disclosed |