Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 19/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 12/20 | 0.71 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.44 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784923 | 0.89 | PIK3CD (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL27658350 | 0.89 | PIK3CD (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL5803254 | 0.87 | PIK3CG (0.62) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL5785803 | 0.85 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL27658380 | 0.84 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL48660 | 0.84 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL48455 | 0.83 | PIK3CD (0.75) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL27658384 | 0.83 | PIK3CD (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL1784080 | 0.83 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB | |
| SCHEMBL1784085 | 0.83 | PIK3CG (0.68) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902375-B2 | Antiallergens; antiarthritic agents; psoriasis; inflammatory bowel disorders; Crohn's disease; sepsis ; antiproliferative agents; anticancer agents; transplant rejection; stroke; antidiabetic agents; restenosis | NOVARTIS AG (CH) | 2011-03-08 | — | — | US | disclosed |