Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749832 | 0.84 | IDO1 (0.38) | EZH2ADH1CADH1A | |
| SCHEMBL18829932 | 0.84 | EZH2 (0.39) | EZH2ADH1CADH1A | |
| SCHEMBL18830512 | 0.83 | EZH2 (0.44) | EZH2 | |
| SCHEMBL20749761 | 0.81 | EZH2 (0.39) | EZH2 | |
| SCHEMBL13280649 | 0.79 | EZH2 (0.52) | EZH2 | |
| SCHEMBL18829951 | 0.79 | EZH2 (0.52) | EZH2 | |
| SCHEMBL13279731 | 0.79 | EZH2 (0.52) | EZH2 | |
| SCHEMBL13280123 | 0.77 | EZH2 (0.52) | EZH2 | |
| SCHEMBL13468542 | 0.76 | EZH2 (0.47) | EZH2 | |
| SCHEMBL15709958 | 0.76 | EZH2 (0.52) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935214-B1 | 1,4-PYRIDONE COMPOUNDS | EPIZYME INC (US) | 2019-02-20 | — | — | EP | disclosed |