Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749743 | 0.84 | EZH2 (0.50) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL20749696 | 0.76 | EZH2 (0.51) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL20749746 | 0.70 | EZH2 (0.50) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL19390929 | 0.67 | EZH2 (0.46) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL19390978 | 0.65 | ERN1 (0.48) | — | |
| SCHEMBL20749728 | 0.65 | EZH2 (0.48) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL19390969 | 0.65 | EZH2 (0.36) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL19390918 | 0.63 | EZH2 (0.51) | CYP2D6CYP2C19EZH2 | |
| SCHEMBL14926660 | 0.61 | CYP2D6 (0.63) | CYP2D6CYP2C19CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL14926658 | 0.61 | CYP3A4 (0.53) | CYP2D6CYP2C19CYP1A2CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935214-B1 | 1,4-PYRIDONE COMPOUNDS | EPIZYME INC (US) | 2019-02-20 | — | — | EP | disclosed |