Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827652 | 0.96 | MAPT (0.49) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL17827653 | 0.86 | MAPT (0.48) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL20751685 | 0.85 | HTR2A (0.37) | MAPTKMT2AALDH1A1HRH3KDM4E | |
| SCHEMBL17827703 | 0.84 | MAPT (0.50) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL17827657 | 0.82 | MAPT (0.42) | MAPTGAAHRH3LMNAKDM4E | |
| SCHEMBL17827658 | 0.78 | SLC2A1 (0.41) | MAPTRAB9AKMT2ACYP3A4LMNA | |
| SCHEMBL17827707 | 0.76 | CHKA (0.42) | MAPTRAB9AGAAHRH3LMNA | |
| SCHEMBL17827663 | 0.74 | MAPT (0.55) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL12520806 | 0.73 | MAPT (0.57) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL17827699 | 0.73 | MAPT (0.53) | MAPTRAB9AKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027608-B1 | SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2019-02-20 | — | — | EP | disclosed |