Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20751652 | 0.85 | MAPT (0.45) | HRH3MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17827657 | 0.82 | MAPT (0.42) | HRH3MAPTHTTKDM4E | |
| SCHEMBL17827652 | 0.81 | MAPT (0.49) | HRH3MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17827707 | 0.76 | CHKA (0.42) | HRH3MAPTSMN1; SMN2HTTKDM4E | |
| SCHEMBL17827658 | 0.74 | SLC2A1 (0.41) | MAPTSMN1; SMN2HTTKHKKMT2A | |
| SCHEMBL17827653 | 0.71 | MAPT (0.48) | HRH3MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17827703 | 0.68 | MAPT (0.50) | HRH3HSD11B1MAPTHTTALDH1A1 | |
| SCHEMBL7961670 | 0.68 | CHKA (0.52) | HRH3MAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23655782 | 0.68 | ADRB1 (0.53) | MAPTSMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL17827637 | 0.68 | SMN1; SMN2 (0.47) | HRH3MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027608-B1 | SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2019-02-20 | — | — | EP | disclosed |