SCHEMBL207523

SCHEMBL207523

CCCCCCCCc1cc(N)ccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.46
GPR84 Q9NQS5 1/20 0.45
TSHR P16473 2/20 0.44
TYR P14679 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX5 P09917 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SRC P12931 1/20 0.44
TLR8 Q9NR97 7/20 0.42
LIPG Q9Y5X9 1/20 0.42
SKP2 Q13309 1/20 0.42
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2018932 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL10345219 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL26104095 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL27992457 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL27796305 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL175665 0.98 TLR8 (0.44) HTR2AGPR84TSHRTYRMEN1
SCHEMBL30227546 0.98 TLR8 (0.44) HTR2AGPR84TSHRTYRMEN1
SCHEMBL30227228 0.92 SKP2 (0.48) HTR2AGPR84TSHRTYRMEN1
SCHEMBL39005 0.92 SKP2 (0.48) HTR2AGPR84TSHRTYRMEN1
SCHEMBL28158536 0.87 TSHR (0.46) HTR2AGPR84TSHRMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1142515-A Anti-ageing agent for composite rubber and preparation thereof NINGYANG FERTILIZER FACTORY SH (CN) 1997-02-12 CN claimed
CN-118541011-A Polymer material for piezoelectric device 株式会社大阪曹达 2024-08-23 CN disclosed
CN-112143433-B Low-dielectric-constant adhesive and preparation method thereof 中瀚新材料科技有限公司 2022-05-24 CN disclosed
WO-2022071281-A1 RUBBER COMPOSITION 株式会社大阪ソーダ 2022-04-07 WO disclosed
WO-2022071279-A1 RUBBER COMPOSITION 株式会社大阪ソーダ 2022-04-07 WO disclosed
CN-109845540-B Agricultural greenhouse film with long-acting dripping, fog-reducing, ageing-resistant and low-temperature-resistant performances 江苏智信塑胶科技有限公司 2021-11-23 CN disclosed
CN-110168060-A Engine oil composition 株式会社ADEKA 2019-08-23 CN disclosed
CN-109845540-A A kind of agricultural canopy film subtracting the ageing-resistant low temperature resistance of mist with long-acting anti-dropping 江苏智信塑胶科技有限公司 2019-06-07 CN disclosed
CN-105531630-B Semi-conductive member for electrophotographic apparatus 株式会社大阪曹达 2019-03-12 CN disclosed
CN-107099071-B tire tread and its manufacturing method 韩国轮胎株式会社 2019-01-08 CN disclosed
EP-0877053-B1 Rubber composition for a conveyor belt MITSUI CHEMICALS INC (JP) 2001-11-14 EP disclosed
EP-0877053-A2 Rubber composition for a conveyor belt Mitsui Chemicals, Inc. (JP) 1998-11-11 EP disclosed
CN-1142515-A Anti-ageing agent for composite rubber and preparation thereof NINGYANG FERTILIZER FACTORY SH (CN) 1997-02-12 CN disclosed
US-4539344-A PUNCTUREPROOF TIRES, BUTYL RUBBER SEALANT ROCKCOR, INC. (US) 1985-09-03 US disclosed
EP-0140298-A1 Substituted 4-hydroxybenzylthioaldehydes and ketones CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed
EP-0116517-A1 Ester or anhydride of substituted 4-(hydroxyphenyl-thio)-succinic acid CIBA-GEIGY AG (CH) 1984-08-22 EP disclosed
US-4241661-A BY COATING WITH AN ANTIOXIDANT TO DECREASE OXIDATIVE HARDENING HERCULES INCORPORATED (US) 1980-12-30 US disclosed
US-4113799-A BUTYL RUBBER, SELF-HEALING TIRES ROCKET RESEARCH CORP. (US) 1978-09-12 US disclosed
US-4048426-A DIISOPRENYL ETHER IN BUTADIENE-STYRENE EMULSION PHILLIPS PETROLEUM COMPANY (US) 1977-09-13 US disclosed
US-3956400-A CROSSLINKING AGENT PHILLIPS PETROLEUM COMPANY (US) 1976-05-11 US disclosed