SCHEMBL2018932

SCHEMBL2018932

CCCCCCc1cc(N)ccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.46
GPR84 Q9NQS5 1/20 0.45
TSHR P16473 2/20 0.44
TYR P14679 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX5 P09917 1/20 0.44
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SRC P12931 1/20 0.44
TLR8 Q9NR97 7/20 0.42
LIPG Q9Y5X9 1/20 0.42
SKP2 Q13309 1/20 0.42
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL207523 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL10345219 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL26104095 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL27992457 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL27796305 1.00 HTR2A (0.46) HTR2AGPR84TSHRTYRMEN1
SCHEMBL175665 0.98 TLR8 (0.44) HTR2AGPR84TSHRTYRMEN1
SCHEMBL30227546 0.98 TLR8 (0.44) HTR2AGPR84TSHRTYRMEN1
SCHEMBL30227228 0.92 SKP2 (0.48) HTR2AGPR84TSHRTYRMEN1
SCHEMBL39005 0.92 SKP2 (0.48) HTR2AGPR84TSHRTYRMEN1
SCHEMBL28158536 0.87 TSHR (0.46) HTR2AGPR84TSHRMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192843-A1 ANTIFOULANT COMPOSITIONS FOR HIGH-SEVERITY PROCESSING OF VINYLIC MONOMER STREAMS ECOLAB USA INC. (US) 2023-10-05 WO claimed
CN-104817459-B The method for generating cyclic aliphatic two-and polyamines for Hydrogenated aromatic two-and polyamines 科思创德国股份有限公司 2019-03-08 CN claimed
CN-108749251-A A kind of graphene superconduction aluminium base board fabrication method 深圳莱必德科技股份有限公司 2018-11-06 CN claimed
CN-107686594-A EVA polymer membranes and its manufacture craft 山东天汇防水股份有限公司 2018-02-13 CN claimed
CN-105153620-B A kind of modified polypropene/super-branched polyimide insulation alloy material and preparation method thereof 江苏省电力公司泰州供电公司 2018-01-12 CN claimed
CN-107266810-A A kind of power distribution overhead conductor insulating sheath 国网四川省电力公司成都供电公司 2017-10-20 CN claimed
CN-102213872-A Pixel electrode panel, liquid crystal display panel assembly and manufacturing method thereof SAMSUNG ELECTRONICS CO LTD 2011-10-12 CN claimed
CN-111542304-B PPD derivatives useful for coloring hair and skin 新加坡国立大学 2023-12-19 CN disclosed
CN-111936559-B Hyperbranched polyesters and their use as wax inhibitors, as pour point depressants, as lubricants or in lubricating oils 巴斯夫欧洲公司 2022-08-30 CN disclosed
WO-2022071279-A1 RUBBER COMPOSITION 株式会社大阪ソーダ 2022-04-07 WO disclosed
WO-2022071281-A1 RUBBER COMPOSITION 株式会社大阪ソーダ 2022-04-07 WO disclosed
WO-2022038011-A1 LUBRICATION BY VAPORIZING AND DEPOSITING AN LUBRICANT ADDITIVE ON A MECHANICAL DEVICE BASF SE (DE) 2022-02-24 WO disclosed
US-11129782-B2 Derivatives of PPD useful for coloring hair and skin NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-09-28 US disclosed
WO-2002042368-A2 METHOD FOR STABILIZING POLYOLEFINS BASF AKTIENGESELLSCHAFT (DE) 2002-05-30 WO disclosed
EP-1181330-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2002-02-27 EP disclosed
CN-1328534-A Stabilised compositions comprising olefins NALCO EXXON ENERGY CHEMICALS C (US) 2001-12-26 CN disclosed
EP-0877053-B1 Rubber composition for a conveyor belt MITSUI CHEMICALS INC (JP) 2001-11-14 EP disclosed
WO-2000066661-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO disclosed
EP-0877053-A2 Rubber composition for a conveyor belt Mitsui Chemicals, Inc. (JP) 1998-11-11 EP disclosed
US-3968080-A VULCANIZING RUBBER MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11129782-B2 Derivatives of PPD useful for coloring hair and skin TST, SDHB, NDUFS3 HTR2A 3021/4885GPR84 3002/4885TSHR 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.