Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129389 | 0.95 | TLR7 (0.48) | TLR7CYP3A4 | |
| SCHEMBL21076543 | 0.91 | TLR7 (0.44) | TLR7ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL7205144 | 0.85 | PDE4A (0.58) | TLR7ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL21076558 | 0.83 | TLR7 (0.57) | TLR7ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL15306090 | 0.83 | NSD2 (0.46) | TLR7ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL10174248 | 0.82 | TLR7 (0.47) | TLR7ADORA2AADORA2BCYP3A4 | |
| SCHEMBL20756520 | 0.81 | TLR7 (0.50) | TLR7 | |
| SCHEMBL4476974 | 0.81 | TLR7 (0.48) | TLR7 | |
| SCHEMBL22404117 | 0.81 | TLR7 (0.50) | TLR7 | |
| SCHEMBL22404116 | 0.80 | TLR7 (0.49) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283482-A1 | BICYCLIC PEPTIDE LIGAND PRR-A CONJUGATES AND USES THEREOF | Bicyclerd Limited (GB) | 2020-09-10 | — | — | US | disclosed |
| WO-2019034868-A1 | BICYCLIC PEPTIDE LIGAND PRR-A CONJUGATES AND USES THEREOF | Bicyclerd Limited (GB) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283482-A1 | BICYCLIC PEPTIDE LIGAND PRR-A CONJUGATES AND USES THEREOF | PRRC2A, GRPR, QRFPR | TLR7 83/4885ADORA2A 730/4885ADORA2B 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.