Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108169 | 0.74 | — | — | |
| SCHEMBL894594 | 0.71 | — | — | |
| SCHEMBL15400895 | 0.69 | — | — | |
| SCHEMBL2520789 | 0.69 | — | — | |
| SCHEMBL20177077 | 0.69 | — | — | |
| SCHEMBL2516598 | 0.68 | TRIM24 (0.33) | TRIM24TRIM33 | |
| SCHEMBL20757758 | 0.68 | CA12 (0.33) | TRIM24TRIM33 | |
| SCHEMBL17796670 | 0.67 | ALDH1A1 (0.33) | TRIM24TRIM33 | |
| SCHEMBL23851895 | 0.67 | TRIM24 (0.32) | TRIM24TRIM33 | |
| SCHEMBL2515686 | 0.67 | SMN1; SMN2 (0.36) | TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034690-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019034692-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |