Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30684250 | 0.75 | IDH1 (0.32) | KCNH2 | |
| SCHEMBL20754868 | 0.75 | IDH1 (0.32) | KCNH2 | |
| SCHEMBL20681193 | 0.72 | HMGCR (0.41) | KCNH2 | |
| SCHEMBL20757449 | 0.70 | AKR1C3 (0.35) | — | |
| SCHEMBL20757284 | 0.68 | METAP2 (0.36) | — | |
| SCHEMBL3488246 | 0.67 | KDM4E (0.43) | KCNH2 | |
| SCHEMBL3490291 | 0.66 | KCNH2 (0.48) | ADORA2BKCNH2 | |
| SCHEMBL20757658 | 0.65 | CYP11B1 (0.40) | MEN1KMT2A | |
| SCHEMBL175252 | 0.64 | KDM4E (0.47) | KCNH2 | |
| SCHEMBL16487535 | 0.64 | SMN1; SMN2 (0.42) | ADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034690-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019034692-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |