Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20759066 | 0.80 | KDM4E (0.33) | ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL10253759 | 0.72 | FFAR3 (0.38) | ALDH1A1KDM4ETSHR | |
| SCHEMBL161143 | 0.71 | — | — | |
| SCHEMBL12379173 | 0.70 | DPP4 (0.33) | DPP4 | |
| SCHEMBL22279660 | 0.69 | — | — | |
| SCHEMBL16267760 | 0.69 | — | — | |
| SCHEMBL31198195 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL5595965 | 0.69 | — | — | |
| SCHEMBL16267390 | 0.69 | — | — | |
| SCHEMBL2625032 | 0.69 | DPP4 (0.34) | ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | KYOWA KIRIN CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| US-10745700-B2 | Nucleic acid conjugate | KYOWA KIRIN CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20190055558-A1 | NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | NSUN3, NSUN2, RNASEH1 | ALDH1A1 1924/4885GAA 670/4885KDM4E 4522/4885 |
| US-10745700-B2 | Nucleic acid conjugate | SLC29A1, NSUN2, H1-2 | ALDH1A1 367/4885GAA 696/4885KDM4E 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.