Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566096 | 1.00 | TLR2 (0.55) | TLR2PTPN1ECE1MDM2ACE | |
| SCHEMBL20759079 | 1.00 | TLR2 (0.55) | TLR2PTPN1ECE1MDM2ACE | |
| SCHEMBL20758974 | 1.00 | TLR2 (0.55) | TLR2PTPN1ECE1MDM2ACE | |
| SCHEMBL30150290 | 0.99 | TLR2 (0.53) | TLR2PTPN1ECE1MDM2 | |
| SCHEMBL30193301 | 0.99 | TLR2 (0.53) | TLR2PTPN1ECE1MDM2 | |
| SCHEMBL30598967 | 0.97 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL30099539 | 0.96 | PTPN1 (0.57) | TLR2PTPN1ECE1ACE | |
| SCHEMBL31212512 | 0.94 | TLR2 (0.59) | TLR2PTPN1MDM2ACE | |
| SCHEMBL31389333 | 0.93 | TLR2 (0.51) | TLR2PTPN1ECE1 | |
| SCHEMBL31138058 | 0.93 | PTPN1 (0.57) | TLR2PTPN1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019033171-A1 | CELL CULTURE SUBSTRATES | MACQUARIE UNIVERSITY (AU) | 2019-02-21 | — | — | WO | disclosed |