Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758974 | 0.97 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL20758846 | 0.97 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL20759079 | 0.97 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL31566096 | 0.97 | TLR2 (0.55) | TLR2PTPN1ECE1 | |
| SCHEMBL30150290 | 0.96 | TLR2 (0.53) | TLR2ITGB3ITGA2BPTPN1ECE1 | |
| SCHEMBL30193301 | 0.96 | TLR2 (0.53) | TLR2ITGB3ITGA2BPTPN1ECE1 | |
| SCHEMBL14374768 | 0.93 | PTPN1 (0.55) | TLR2PTPN1 | |
| SCHEMBL31212512 | 0.93 | TLR2 (0.59) | TLR2PTPN1 | |
| SCHEMBL30099539 | 0.93 | PTPN1 (0.57) | TLR2PTPN1ECE1 | |
| SCHEMBL19423749 | 0.91 | TLR2 (0.55) | TLR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005739-B | Polypeptide APH229 of drug-resistant strain, preparation method and application thereof | 南京华盖制药有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118005741-B | Antibacterial polypeptide AP16A and preparation method and application thereof | 中国药科大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118005741-A | Antibacterial polypeptide AP16A and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005739-A | Polypeptide APH229 of drug-resistant strain, preparation method and application thereof | 南京华盖制药有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116874614-B | Antibacterial polypeptide APH171 with high activity and low cracking effect, and preparation method and application thereof | 南京华盖制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116874614-A | Antibacterial polypeptide APH171 with high activity and low cracking effect, and preparation method and application thereof | 南京华盖制药有限公司 | 2023-10-13 | — | — | CN | disclosed |