⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615361 | 0.81 | TSHR (0.57) | — | |
| SCHEMBL8257596 | 0.80 | TSHR (0.50) | — | |
| SCHEMBL6667055 | 0.76 | — | — | |
| SCHEMBL9219488 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL12997424 | 0.73 | — | — | |
| SCHEMBL11895137 | 0.71 | TSHR (0.58) | — | |
| SCHEMBL28619980 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL17072517 | 0.71 | TSHR (0.44) | — | |
| Dimethyl Succinate SCHEMBL28054469 | 0.71 | TSHR (1.00) | — | |
| Dimethyl Succinate SCHEMBL10213 | 0.71 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-20200331850-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-10-22 | — | — | US | disclosed |
| WO-2019034696-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |