Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615361 | 0.91 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL8257596 | 0.81 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL17072517 | 0.80 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL28619980 | 0.80 | TSHR (0.46) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL11895137 | 0.77 | TSHR (0.58) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL17072512 | 0.76 | TSHR (0.40) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL18534097 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL17072510 | 0.74 | TSHR (0.39) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL20760739 | 0.74 | — | — | |
| SCHEMBL17072507 | 0.72 | TSHR (0.38) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7300451-A | — | — | None | — | — | JP | disclosed |
| JP-H07300451-A | NEW SULFONE COMPOUND | NIPPON SHOKUBAI CO LTD | 1995-11-14 | — | — | JP | disclosed |