Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14912522 | 0.80 | KDM4E (0.46) | MEN1KMT2APOLBKDM4EHPGD | |
| SCHEMBL9203028 | 0.78 | MEN1 (0.52) | MEN1KMT2APOLBHPGDAR | |
| SCHEMBL20757925 | 0.75 | CA12 (0.43) | MEN1KMT2APOLBKDM4EHPGD | |
| SCHEMBL20754556 | 0.74 | KDM4E (0.38) | KDM4EHPGDALDH1A1GAA | |
| SCHEMBL23328665 | 0.73 | CA12 (0.41) | MEN1KMT2APOLBKDM4EHPGD | |
| SCHEMBL20754811 | 0.70 | LMNA (0.47) | MEN1KMT2APOLBKDM4EHPGD | |
| SCHEMBL14912963 | 0.67 | SMN1; SMN2 (0.47) | KDM4EHPGDSMN1; SMN2TSHRGAA | |
| SCHEMBL12108494 | 0.66 | KDM4E (0.66) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23880241 | 0.65 | MAP3K14 (0.37) | KMT2AHPGD | |
| SCHEMBL14930399 | 0.65 | SMN1; SMN2 (0.51) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034688-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |