Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | CDC14B | O60729 | 2/20 | 0.33 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820384 | 0.90 | ALOX5 (0.53) | ALOX5PRKDCMMP12MMP13GGPS1 | |
| SCHEMBL18820368 | 0.89 | ALOX5 (0.56) | ALOX5PRKDCMMP12MMP13GGPS1 | |
| SCHEMBL18820374 | 0.89 | MEN1 (0.41) | ALOX5PRKDCMMP12MMP13PLA2G2A | |
| SCHEMBL18820568 | 0.86 | ALOX5 (0.49) | ALOX5PRKDCGGPS1PLA2G2APLA2G4A | |
| SCHEMBL18820370 | 0.85 | ALOX5 (0.41) | ALOX5PRKDCMMP12MMP13PLA2G2A | |
| SCHEMBL18820371 | 0.85 | ALOX5 (0.57) | ALOX5PRKDCGGPS1CDC14BCDC14A | |
| SCHEMBL20762353 | 0.85 | ALOX5 (0.44) | ALOX5PRKDCGGPS1PLA2G2APLA2G4A | |
| SCHEMBL18820780 | 0.84 | ALOX5 (0.58) | ALOX5PRKDCGGPS1CDC14BCDC14A | |
| SCHEMBL18252561 | 0.83 | ALOX5 (0.61) | ALOX5PRKDCGGPS1PLA2G2APLA2G4A | |
| SCHEMBL18252607 | 0.83 | ALOX5 (0.61) | ALOX5PRKDCGGPS1PLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885PRKDC 4071/4885MMP12 1668/4885 |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885PRKDC 4071/4885MMP12 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.