Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 10/20 | 0.33 |
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | CA5A | P35218 | 10/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 10/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22571722 | 0.87 | F2 (0.50) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20762012 | 0.87 | F2 (0.50) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28471311 | 0.75 | F2 (0.42) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL15172850 | 0.69 | KMT2A (0.68) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18885076 | 0.69 | ALDH1A1 (0.49) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2385301 | 0.69 | KMT2A (0.68) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18885074 | 0.69 | ALDH1A1 (0.49) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4484995 | 0.69 | KMT2A (0.68) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1696817 | 0.69 | KMT2A (0.68) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5442172 | 0.69 | KMT2A (0.68) | L3MBTL1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034696-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |