⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493141 | 0.86 | — | — | |
| SCHEMBL15065771 | 0.78 | — | — | |
| Oxalic Acid SCHEMBL5372508 | 0.73 | CA4 (0.30) | — | |
| Ethylene Glycol SCHEMBL11417061 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL15840107 | 0.65 | TSHR (0.30) | — | |
| SCHEMBL17254415 | 0.65 | TSHR (0.30) | — | |
| SCHEMBL94048 | 0.63 | — | — | |
| Ethylene Glycol SCHEMBL9756248 | 0.62 | TSHR (0.46) | — | |
| Ethylene Glycol SCHEMBL4769225 | 0.62 | TSHR (0.46) | — | |
| Ethylene Glycol SCHEMBL3171689 | 0.62 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640730-B1 | PROCESSES FOR PREPARATION OF EVEROLIMUS AND INTERMEDIATES THEREOF | BIOCON LTD (IN) | 2019-08-07 | — | — | EP | claimed |
| US-9079921-B2 | Processes for preparation of Everolimus and intermediates thereof | BIOCON LIMITED (IN) | 2015-07-14 | — | — | US | claimed |
| EP-2640730-B1 | PROCESSES FOR PREPARATION OF EVEROLIMUS AND INTERMEDIATES THEREOF | BIOCON LTD (IN) | 2019-08-07 | — | — | EP | disclosed |
| US-9079921-B2 | Processes for preparation of Everolimus and intermediates thereof | BIOCON LIMITED (IN) | 2015-07-14 | — | — | US | disclosed |
| EP-1856129-B1 | 39-DESMETHOXY DERIVATIVES OF RAPAMYCIN | BIOTICA TECH LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| US-8008318-B2 | 39-desmethoxy derivatives of rapamycin | BIOTICA TECHNOLOGY LIMITED (GB) | 2011-08-30 | — | — | US | disclosed |
| US-7897608-B2 | 39-desmethoxy-39-methyl derivatives of rapamycin | BIOTICA TECHNOLOGY LIMITED (GB) | 2011-03-01 | — | — | US | disclosed |
| US-20100081682-A1 | 39-Desmethoxy Derivatives of Rapamycin | BIOTICA TECHNOLOGY LIMITED (GB) | 2010-04-01 | — | — | US | disclosed |
| US-7648996-B2 | 39-desmethoxy derivatives of rapamycin | BIOTICA TECHNOLOGY LIMITED (GB) | 2010-01-19 | — | — | US | disclosed |
| US-20090209572-A1 | 36-Des(3-Methoxy-4-Hydroxycyclohexyl) 36-(3-Hydroxycycloheptyl) Derivatives of Rapamycin for the Treatment of Cancer and Other Disorders | BIOTICA TECHNOLOGY LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| US-20090176819-A1 | 39-Desmethoxy-39-Methyl Derivatives of Rapamycin | WYETH (US) | 2009-07-09 | — | — | US | disclosed |
| EP-2027130-A1 | 36 -DES (3 -METHOXY-4 -HYDROXYCYCLOHEXYL) 36 - (3 -HYDROXYCYCLOHEPTYL) DERIVATIVES OF RAPAMYCIN FOR THE TREATMENT OF CANCER AND OTHER DISORDERS | Biotica Technology Limited (GB) | 2009-02-25 | — | — | EP | disclosed |
| EP-2027131-A1 | 39-DESMETHOXY-39-METHYL DERIVATIVES OF RAPAMYCIN. | Biotica Technology Limited (GB) | 2009-02-25 | — | — | EP | disclosed |
| US-20080188511-A1 | 39-Desmethoxy Derivatives of Rapamycin | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-08-07 | — | — | US | disclosed |
| WO-2007135397-A1 | 36 -DES (3 -METHOXY-4 -HYDROXYCYCLOHEXYL) 36 - (3 -HYDROXYCYCLOHEPTYL) DERIVATIVES OF RAPAMYCIN FOR THE TREATMENT OF CANCER AND OTHER DISORDERS | BIOTICA TECHNOLOGY LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135411-A1 | 39-DESMETHOXY-39-METHYL DERIVATIVES OF RAPAMYCIN. | BIOTICA TECHNOLOGY LTD. (GB) | 2007-11-29 | — | — | WO | disclosed |
| EP-1856129-A1 | 39-DESMETHOXY DERIVATIVES OF RAPAMYCIN | Biotica Technology Limited (GB) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006095185-A1 | 39-DESMETHOXY DERIVATIVES OF RAPAMYCIN | BIOTICA TECHNOLOGY LIMITED (GB) | 2006-09-14 | — | — | WO | disclosed |