Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764223 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL4896863 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL4893495 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL10747713 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL23389159 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL8337079 | 0.79 | KDM4E (0.60) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL23389161 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL4894773 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ELMNARECQLHPGD | |
| SCHEMBL4896975 | 0.78 | KDM4E (0.67) | ALDH1A1KDM4ELMNARECQLHPGD | |
| Hydrochloric Acid SCHEMBL23389229 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNARECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795162-B2 | Modulators of the estrogen-related receptor | SAINT LOUIS UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-20200247792-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-08-06 | — | — | US | disclosed |
| WO-2019036562-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247792-A1 | ERR INVERSE AGONISTS | ESRRA, ESRRB, ESR2 | ALDH1A1 1354/4885KDM4E 1194/4885LMNA 4539/4885 |
| US-11795162-B2 | Modulators of the estrogen-related receptor | ESR2, GPER1, ESRRG | ALDH1A1 2485/4885KDM4E 1278/4885LMNA 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.