Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK14 | O94921 | 2/20 | 0.47 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.46 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MB | P02144 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665103 | 0.87 | NMT1 (0.58) | CDK14CCNYSMN1; SMN2HTTNR4A1 | |
| SCHEMBL13067824 | 0.86 | EGFR (0.47) | CDK14CCNYSMN1; SMN2NR4A1PIP4K2A | |
| SCHEMBL13389249 | 0.85 | EGFR (0.55) | CDK14CCNYSMN1; SMN2PIP4K2APIP4K2B | |
| SCHEMBL16665568 | 0.84 | PIP4K2A (0.50) | CDK14CCNYNR4A1PIP4K2APIP4K2B | |
| SCHEMBL22106124 | 0.84 | CDK14 (0.46) | CDK14CCNYSMN1; SMN2NR4A1PIP4K2A | |
| SCHEMBL23336402 | 0.84 | CDK14 (0.46) | CDK14CCNYSMN1; SMN2NR4A1PIP4K2A | |
| SCHEMBL17141876 | 0.84 | PIP4K2A (0.50) | CDK14CCNYNR4A1PIP4K2APIP4K2B | |
| SCHEMBL20093336 | 0.83 | EGFR (0.56) | CDK14CCNYSMN1; SMN2L3MBTL1NR4A1 | |
| SCHEMBL18113964 | 0.83 | KDM4E (0.49) | CDK14CCNYSMN1; SMN2L3MBTL1PIP4K2A | |
| SCHEMBL23336317 | 0.83 | KDM4E (0.49) | CDK14CCNYSMN1; SMN2L3MBTL1PIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019035866-A1 | COMPOSITIONS AND METHODS FOR TREATING TUBEROUS SCLEROSIS COMPLEX | THE BRIGHAM & WOMEN'S HOSPITAL, INC. (US) | 2019-02-21 | — | — | WO | disclosed |