Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK14 | O94921 | 2/20 | 0.46 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.44 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 8/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22106124 | 0.85 | CDK14 (0.46) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL20764166 | 0.84 | CDK14 (0.47) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL16665103 | 0.84 | NMT1 (0.58) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL13067824 | 0.83 | EGFR (0.47) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL13389249 | 0.83 | EGFR (0.55) | CDK14CCNYPIP4K2APIP4K2BEGFR | |
| SCHEMBL16665568 | 0.82 | PIP4K2A (0.50) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL17141876 | 0.82 | PIP4K2A (0.50) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL20093336 | 0.81 | EGFR (0.56) | CDK14CCNYPIP4K2APIP4K2BNR4A1 | |
| SCHEMBL18113964 | 0.81 | KDM4E (0.49) | CDK14CCNYPIP4K2APIP4K2BCDK7 | |
| SCHEMBL23336317 | 0.81 | KDM4E (0.49) | CDK14CCNYPIP4K2APIP4K2BCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057956-B1 | POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | DANA FARBER CANCER INST INC (US) | 2021-05-05 | — | — | EP | disclosed |