SCHEMBL207642

SCHEMBL207642

c1ccc(Oc2cc[nH]n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.53
LTA4H P09960 4/20 0.48
TSHR P16473 1/20 0.48
BCAT2 O15382 1/20 0.44
HTT P42858 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 3/20 0.40
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
MAPK1 P28482 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 3/20 0.38
LOXL2 Q9Y4K0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28313179 0.94 HAO1 (0.48) HAO1LTA4HTSHRBCAT2HTT
Tert-Butyl Formate SCHEMBL27726909 0.82 TDP1 (0.39) HAO1LTA4HTSHRBCAT2HTT
SCHEMBL27848864 0.78 MEN1 (0.57) HAO1TSHRHTTALDH1A1CYP2C9
SCHEMBL27082204 0.78 HAO1 (0.33) HAO1
SCHEMBL28272734 0.74 HAO1 (0.33) HAO1KMT2AMEN1
SCHEMBL1817017 0.72 KDM4E (0.43) LTA4HTSHRHTTALDH1A1CYP1A2
SCHEMBL3364770 0.71 NPC1 (0.50) HAO1LTA4HTSHRNPC1RAB9A
SCHEMBL1009470 0.71 CYP1A2 (0.48) HAO1TSHRBCAT2ALDH1A1CYP1A2
SCHEMBL31374417 0.71 KDM4E (0.42) LTA4HTSHRHTTALDH1A1CYP1A2
SCHEMBL4276104 0.70 BCAT2 (0.75) HAO1LTA4HTSHRBCAT2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
CN-101323592-B Substituted phenyl pyrazole ether compounds and application thereof SINOCHEM GROUP CO LTD 2011-07-27 CN claimed
CN-101323592-A Substituted phenyl pyrazole ether compounds and application thereof SHENYANG RES INST CHEMICAL IND (CN) 2008-12-17 CN claimed
EP-1074551-B1 Phenylpyrazoles with a herbicidal activity ISAGRO RICERCA SRL (IT) 2003-03-26 EP claimed
US-6265351-B1 CONTROLLING WEEDS IN THE AGRONOMIC FIELD. ISAGRO RICERCA S.R.L. (IT) 2001-07-24 US claimed
EP-1074551-A2 Phenylpyrazoles with a herbicidal activity Isagro Ricerca S.r.l. (IT) 2001-02-07 EP claimed
US-5256626-A Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds MONSANTO COMPANY (US) 1993-10-26 US claimed
US-5185025-A SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES MONSANTO COMPANY (US) 1993-02-09 US claimed
US-5045106-A 3-phenoxypyrazole MONSANTO COMPANY (US) 1991-09-03 US claimed
US-4964895-A Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides MONSANTO COMPANY (US) 1990-10-23 US claimed
EP-0371947-A1 Substituted pyrazoles and their use as herbicides Monsanto Company (US) 1990-06-06 EP claimed
EP-0370990-A1 Herbicidal substituted pyrazoles MONSANTO COMPANY (US) 1990-05-30 EP claimed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP claimed
JP-2193976-A None JP disclosed
JP-2193977-A None JP disclosed
JP-1025764-A None JP disclosed
CN-1033457-A 3-(4-nitrophenoxy) pyrazoles that replaces and as the purposes of weedicide MONSANTO CO (US) 1989-06-21 CN disclosed
EP-0304409-A1 5-Heterocyclic-substituted oxazolidine haloacetamides MONSANTO COMPANY (US) 1989-02-22 EP disclosed
EP-0295233-A2 Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides Monsanto Company (US) 1988-12-14 EP disclosed
US-4258170-A Polyphosphazene polymers containing pyrazole or imidazole substituents THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-03-24 US disclosed