Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 8/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764060 | 0.88 | ESRRG (1.00) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20764032 | 0.87 | ESRRG (0.79) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22311822 | 0.85 | ESRRG (0.77) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20764033 | 0.84 | ESRRG (0.74) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20764054 | 0.79 | ESRRG (0.66) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20764261 | 0.78 | ESRRG (0.78) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22311795 | 0.77 | ESRRG (1.00) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31610027 | 0.75 | ESRRG (0.70) | ESRRGNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5844175 | 0.74 | HPGD (0.66) | ESRRGRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL31337226 | 0.73 | NPC1 (0.68) | ESRRGNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036562-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |