Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 10/20 | 0.78 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.78 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.75 |
| ▸ | RAB9A | P51151 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764089 | 0.87 | ESRRG (1.00) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764244 | 0.87 | ESRRG (1.00) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764080 | 0.86 | ESRRG (0.78) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764028 | 0.85 | PTPN11 (0.85) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL22311823 | 0.84 | ESRRG (0.77) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL22311792 | 0.84 | ESRRG (0.77) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764061 | 0.83 | NPC1 (0.75) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764002 | 0.80 | ESRRG (1.00) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL24573944 | 0.79 | RAB9A (0.76) | ESRRGPTPN11PTPN2NPC1RAB9A | |
| SCHEMBL20764355 | 0.78 | ESRRG (0.79) | ESRRGPTPN11PTPN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036562-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |