Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510225 | 0.93 | TLR7 (0.74) | TLR7 | |
| SCHEMBL20764410 | 0.92 | TLR7 (0.59) | TLR7 | |
| SCHEMBL7207331 | 0.89 | TLR7 (0.70) | TLR7 | |
| SCHEMBL20764265 | 0.89 | TLR7 (0.62) | TLR7IL6 | |
| SCHEMBL20764366 | 0.88 | TLR7 (0.58) | TLR7IL6 | |
| SCHEMBL21449010 | 0.88 | TLR7 (0.62) | TLR7 | |
| SCHEMBL4463674 | 0.88 | TLR7 (0.59) | TLR7 | |
| SCHEMBL10174289 | 0.87 | TLR7 (0.64) | TLR7 | |
| SCHEMBL7205092 | 0.87 | TLR7 (0.66) | TLR7 | |
| SCHEMBL24366070 | 0.86 | TLR7 (0.67) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913741-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
| US-20200392137-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY | 2020-12-17 | — | — | US | disclosed |
| US-10793569-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200255429-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY | 2020-08-13 | — | — | US | disclosed |
| US-10689382-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-23 | — | — | US | disclosed |
| US-10508115-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-12-17 | — | — | US | disclosed |
| US-20190055247-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10508115-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
| US-20200255429-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
| US-10793569-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
| US-10913741-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 595/4885 |
| US-20190055247-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
| US-20200392137-A1 | TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING HETEROATOM-LINKED AROMATIC MOIETIES, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
| US-10689382-B2 | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor | TLR7, TLR1, TLR8 | TLR7 1/4885IL6 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.