Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 5/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | NRP1 | O14786 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069733 | 0.90 | OPRM1 (0.54) | OPRM1GRB2F2NTSR2NTSR1 | |
| SCHEMBL30286828 | 0.87 | OPRM1 (0.52) | OPRM1GRB2F2NTSR2NTSR1 | |
| SCHEMBL30080797 | 0.86 | OPRM1 (0.51) | OPRM1GRB2F2NTSR2NTSR1 | |
| SCHEMBL29471807 | 0.86 | OPRM1 (0.51) | OPRM1CAPN1BDKRB2GRB2F2 | |
| SCHEMBL29591635 | 0.86 | OPRM1 (0.52) | OPRM1BDKRB2GRB2F2NTSR2 | |
| SCHEMBL29590494 | 0.85 | OPRM1 (0.51) | OPRM1BDKRB2GRB2F2NTSR2 | |
| SCHEMBL29630459 | 0.85 | OPRM1 (0.53) | OPRM1BDKRB2F2NTSR2NTSR1 | |
| SCHEMBL29881564 | 0.84 | OPRM1 (0.59) | OPRM1CAPN1BDKRB2GRB2F2 | |
| SCHEMBL29886892 | 0.84 | OPRM1 (0.47) | OPRM1CAPN1OPRD1 | |
| SCHEMBL29380256 | 0.84 | OPRM1 (0.46) | OPRM1F2NTSR2NTSR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672626-A1 | COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS | Onkologix Ltd (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038671-A1 | COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS | ONKOLOGIX LTD (US) | 2019-02-28 | — | — | WO | disclosed |