Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MYC | P01106 | 3/20 | 0.42 |
| ▸ | MAX | P61244 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625926 | 0.87 | MEN1 (0.49) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL20764575 | 0.87 | MEN1 (0.49) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL17775441 | 0.75 | MEN1 (0.47) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL16369625 | 0.74 | CTSV (0.48) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL17775433 | 0.72 | MYC (0.54) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL16369635 | 0.71 | MYC (0.62) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL28511094 | 0.69 | MYC (0.51) | CTSVCTSLMAPTMYCMAX | |
| SCHEMBL6276534 | 0.69 | MEN1 (0.47) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL17403333 | 0.69 | MAPT (0.59) | CTSVCTSLMAPTKMT2AMEN1 | |
| SCHEMBL31237027 | 0.69 | MAPT (0.47) | MAPTKMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672937-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |