Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764803 | 0.90 | DUT (0.39) | KDM4ETDP1DUTALDH1A1MAPT | |
| SCHEMBL3127757 | 0.83 | KDM4E (0.37) | KDM4ETDP1DUTALDH1A1MAPT | |
| SCHEMBL1246103 | 0.80 | DUT (0.35) | DUT | |
| SCHEMBL12970675 | 0.80 | DUT (0.35) | DUT | |
| SCHEMBL1247752 | 0.80 | DUT (0.35) | DUTALDH1A1HTTKMT2A | |
| SCHEMBL24197440 | 0.80 | DUT (0.38) | DUT | |
| SCHEMBL2142085 | 0.80 | DUT (0.35) | DUTALDH1A1MAPTADRA1DADRA1A | |
| SCHEMBL2037958 | 0.77 | KDM4E (0.35) | KDM4ETDP1ALDH1A1MAPTHTT | |
| SCHEMBL19475200 | 0.77 | DUT (0.32) | DUT | |
| SCHEMBL2139606 | 0.76 | DUT (0.35) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |