SCHEMBL20764845

SCHEMBL20764845

F[C](F)F.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1805 0.89
SCHEMBL27427251 0.89
SCHEMBL27853443 0.89
SCHEMBL28871336 0.80
SCHEMBL919639 0.80
Hydrogen Sulfide SCHEMBL1485809 0.80
SCHEMBL11510811 0.80
Hydroxyl Radical SCHEMBL5493220 0.80
Lithium SCHEMBL30580717 0.80
SCHEMBL6408104 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080030-B Continuous production process of liquid lithium hexafluorophosphate 山东江岳科技开发股份有限公司 2025-01-21 CN claimed
CN-119080030-A Continuous production process of liquid lithium hexafluorophosphate 山东江岳科技开发股份有限公司 2024-12-06 CN claimed
CN-118344238-A Method for preparing 1-chloro-3, 3-trifluoropropyl substituted aromatic compound under illumination condition 四川轻化工大学 2024-07-16 CN claimed
CN-118164971-A Method for preparing carbostyril 四川大学 2024-06-11 CN claimed
CN-117702143-A Preparation method of amine trifluoromethyl derivative of electrochemical alkylene oxide 南京德川医药科技有限公司 2024-03-15 CN claimed
CN-117624260-A 2-deoxy-2-trifluoromethyl substituted glycosyl o-alkynyl benzoate compound, preparation method and application thereof 国科大杭州高等研究院 2024-03-01 CN claimed
CN-117384097-A Preparation and purification method of 4, 5-dicyano-2-trifluoromethyl imidazole 浙江大学 2024-01-12 CN claimed
CN-116947780-A Preparation method of thiazolidine-4-thioketone derivative 华侨大学 2023-10-27 CN claimed
CN-116836104-A Blue light induced method for hydrogen trifluoromethyl of alkynyl compound 湖南大学 2023-10-03 CN claimed
CN-114108013-B Electrochemical synthesis method of trifluoromethyl substituted polycyclic quinazolinone derivative 江苏信和生物医药有限公司 2023-09-22 CN claimed
CN-111825580-A Method for synthesizing aromatic hydrocarbon trifluoromethylthio compound 南京理工大学 2020-10-27 CN claimed
CN-111704587-A Synthetic method of trifluoromethyl 1, 3-oxazine compound 遵义医科大学 2020-09-25 CN claimed
CN-110590774-B Trifluoromethyl imidazole condensed ring compound and preparation method thereof 河南中医药大学 2020-09-08 CN claimed
CN-106892800-B Preparation method and application of unactivated olefin hydrofluoromethylation 湖北工程学院 2020-08-28 CN claimed
CN-111499543-A α -fluoroalkyl- β -amidoketone compound and preparation method thereof 南京工业大学 2020-08-07 CN claimed
CN-109972165-B Electrochemical preparation method of β -trifluoromethyl amide compound 五邑大学 2020-07-17 CN claimed
CN-111303089-A Preparation method of α -halogenated trifluoromethyl substituted alkane 河北科技大学 2020-06-19 CN claimed
CN-111269074-A Preparation method of α -halogenated trifluoromethyl substituted alkane 河北科技大学 2020-06-12 CN claimed
CN-111087352-A Preparation method of 3-trifluoroalkyl quinoxalinone compound 曲阜师范大学 2020-05-01 CN claimed
CN-110903233-A 3, 3' -diindolylmethane derivatives, and synthesis method and biological activity thereof 湖南大学 2020-03-24 CN claimed