SCHEMBL20764852

SCHEMBL20764852

CC(C)(C)OC(=O)N1CCC(Oc2cncnc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 14/20 0.56
NPBWR1 P48145 1/20 0.48
MCHR1 Q99705 1/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23311655 0.85 GPR119 (0.55) GPR119NPBWR1MCHR1
SCHEMBL639943 0.85 GPR119 (0.63) GPR119
SCHEMBL20137483 0.85 GPR119 (0.52) GPR119NPBWR1MCHR1
SCHEMBL21606937 0.85 GPR119 (0.52) GPR119NPBWR1MCHR1
SCHEMBL19504087 0.84 GPR119 (0.54) GPR119NPBWR1MCHR1HPGD
SCHEMBL4713304 0.84 GPR119 (0.62) GPR119
SCHEMBL4264039 0.84 GPR119 (0.51) GPR119NPBWR1MCHR1
SCHEMBL2775170 0.84 GPR119 (0.54) GPR119
SCHEMBL18475482 0.84 GPR119 (0.51) GPR119NPBWR1MCHR1
SCHEMBL14004872 0.84 GPR119 (0.51) GPR119NPBWR1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11213525-B2 Linear glycosidase inhibitors ASCENEURON SA (CH) 2022-01-04 US disclosed
US-11213525-B2 Linear glycosidase inhibitors ASCENEURON SA (CH) 2022-01-04 US disclosed
US-20210077488-A1 LINEAR GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-03-18 US disclosed
US-20210077488-A1 LINEAR GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-03-18 US disclosed
EP-3672959-A1 LINEAR GLYCOSIDASE INHIBITORS Asceneuron SA (CH) 2020-07-01 EP disclosed
WO-2019037860-A1 LINEAR GLYCOSIDASE INHIBITORS Asceneuron S.A. (CH) 2019-02-28 WO disclosed
WO-2019037860-A1 LINEAR GLYCOSIDASE INHIBITORS Asceneuron S.A. (CH) 2019-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11213525-B2 Linear glycosidase inhibitors ENGASE, GAA, GLA GPR119 620/4885NPBWR1 945/4885MCHR1 3093/4885
US-20210077488-A1 LINEAR GLYCOSIDASE INHIBITORS ENGASE, GAA, GLA GPR119 620/4885NPBWR1 945/4885MCHR1 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.