SCHEMBL20765405

SCHEMBL20765405

C[C@@H]1COCCN1c1cc(-c2ccc(S(C)(=O)=O)cc2C(F)(F)F)[nH]c(=O)c1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633708 1.00 PIK3C3 (0.72) PIK3C3
SCHEMBL22654565 1.00 PIK3C3 (0.72) PIK3C3
SCHEMBL22654569 0.90 PIK3C3 (0.69) PIK3C3
SCHEMBL29633644 0.90 PIK3C3 (0.69) PIK3C3
SCHEMBL30288864 0.90 PIK3C3 (0.69) PIK3C3
SCHEMBL22654572 0.90 PIK3C3 (0.69) PIK3C3
SCHEMBL20777027 0.90 PIK3C3 (0.69) PIK3C3
SCHEMBL24470269 0.84 PIK3C3 (1.00) PIK3C3
SCHEMBL19272649 0.84 PIK3C3 (1.00) PIK3C3
SCHEMBL19259530 0.84 PIK3C3 (1.00) PIK3C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384180-A1 COMBINATION THERAPY OF VPS34 INHIBITORS AND STING AGONIST FOR USE IN THE TREATMENT OF CANCER Deciphera Pharmaceuticals, LLC (US) 2024-06-19 EP claimed
CN-118201619-A Combination therapy of VPS34 inhibitors with STING agonists for the treatment of cancer 德西费拉制药有限责任公司 2024-06-14 CN claimed
WO-2023019259-A1 COMBINATION THERAPY OF VPS34 INHIBITORS AND STING AGONIST FOR USE IN THE TREATMENT OF CANCER DECIPHERA PHARMACEUTICALS, LLC (US) 2023-02-16 WO claimed
EP-4384180-A1 COMBINATION THERAPY OF VPS34 INHIBITORS AND STING AGONIST FOR USE IN THE TREATMENT OF CANCER Deciphera Pharmaceuticals, LLC (US) 2024-06-19 EP disclosed
CN-118201619-A Combination therapy of VPS34 inhibitors with STING agonists for the treatment of cancer 德西费拉制药有限责任公司 2024-06-14 CN disclosed
US-20230234949-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2023-07-27 US disclosed
US-20230234949-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2023-07-27 US disclosed
US-20230234949-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2023-07-27 US disclosed
CN-116462674-A Morpholinyl pyridone compounds 思普瑞特生物科学公司 2023-07-21 CN disclosed
CN-116444510-A Morpholinyl pyridone compounds 思普瑞特生物科学公司 2023-07-18 CN disclosed
CN-111108102-B Morpholinyl pyridone compounds 思普瑞特生物科学公司 2023-04-28 CN disclosed
EP-4056569-A1 MORPHOLINYLPYRIDONE COMPOUNDS Sprint Bioscience AB (SE) 2022-09-14 EP disclosed
EP-3672962-B1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2022-01-26 EP disclosed
EP-3672962-B1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2022-01-26 EP disclosed
US-20200361922-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2020-11-19 US disclosed
US-20200361922-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2020-11-19 US disclosed
EP-3672962-A1 MORPHOLINYLPYRIDONE COMPOUNDS Sprint Bioscience AB (SE) 2020-07-01 EP disclosed
CN-111108102-A Morpholinopyridone compounds 思普瑞特生物科学公司 2020-05-05 CN disclosed
WO-2019038390-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2019-02-28 WO disclosed
WO-2019038390-A1 MORPHOLINYLPYRIDONE COMPOUNDS SPRINT BIOSCIENCE AB (SE) 2019-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361922-A1 MORPHOLINYLPYRIDONE COMPOUNDS MAP1B, RRP12, MYT1 PIK3C3 3743/4885
US-20230234949-A1 MORPHOLINYLPYRIDONE COMPOUNDS MAP1B, RRP12, MYT1 PIK3C3 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.