SCHEMBL29633644

SCHEMBL29633644

CC1COCCN1c1cc(-c2ccc(S(=O)(=O)N(C)C)cc2C(F)(F)F)[nH]c(=O)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22654569 1.00 PIK3C3 (0.69) PIK3C3
SCHEMBL22654572 1.00 PIK3C3 (0.69) PIK3C3
SCHEMBL30288864 1.00 PIK3C3 (0.69) PIK3C3
SCHEMBL20765405 0.90 PIK3C3 (0.72) PIK3C3
SCHEMBL22654565 0.90 PIK3C3 (0.72) PIK3C3
SCHEMBL29633708 0.90 PIK3C3 (0.72) PIK3C3
SCHEMBL20777027 0.88 PIK3C3 (0.69) PIK3C3
SCHEMBL24470269 0.82 PIK3C3 (1.00) PIK3C3
SCHEMBL19272649 0.82 PIK3C3 (1.00) PIK3C3
SCHEMBL19259530 0.82 PIK3C3 (1.00) PIK3C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384180-A1 COMBINATION THERAPY OF VPS34 INHIBITORS AND STING AGONIST FOR USE IN THE TREATMENT OF CANCER Deciphera Pharmaceuticals, LLC (US) 2024-06-19 EP claimed
EP-4251165-A1 MORPHOLINO DERIVATIVES AS VSP34 INHIBITORS FOR USE IN THE TREATMENT OF A VIRAL INFECTION Deciphera Pharmaceuticals, LLC (US) 2023-10-04 EP claimed
WO-2023019259-A1 COMBINATION THERAPY OF VPS34 INHIBITORS AND STING AGONIST FOR USE IN THE TREATMENT OF CANCER DECIPHERA PHARMACEUTICALS, LLC (US) 2023-02-16 WO claimed
WO-2022115558-A1 MORPHOLINO DERIVATIVES AS VSP34 INHIBITORS FOR USE IN THE TREATMENT OF A VIRAL INFECTION DECIPHERA PHARMACEUTICALS, LLC (US) 2022-06-02 WO claimed
EP-4251165-A1 MORPHOLINO DERIVATIVES AS VSP34 INHIBITORS FOR USE IN THE TREATMENT OF A VIRAL INFECTION Deciphera Pharmaceuticals, LLC (US) 2023-10-04 EP disclosed
WO-2022115558-A1 MORPHOLINO DERIVATIVES AS VSP34 INHIBITORS FOR USE IN THE TREATMENT OF A VIRAL INFECTION DECIPHERA PHARMACEUTICALS, LLC (US) 2022-06-02 WO disclosed