Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673246 | 1.00 | DNMT3A (0.46) | DNMT3ATP53GPR119HDAC1HDAC2 | |
| SCHEMBL20778648 | 1.00 | DNMT3A (0.46) | DNMT3ATP53GPR119HDAC1HDAC2 | |
| SCHEMBL20794795 | 1.00 | DNMT3A (0.46) | DNMT3ATP53GPR119HDAC1HDAC2 | |
| SCHEMBL29673228 | 1.00 | DNMT3A (0.46) | DNMT3ATP53GPR119HDAC1HDAC2 | |
| SCHEMBL29673216 | 1.00 | DNMT3A (0.46) | DNMT3ATP53GPR119HDAC1HDAC2 | |
| SCHEMBL517515 | 0.90 | USP30 (0.53) | TP53GPR119USP30TACR1 | |
| SCHEMBL5768083 | 0.90 | USP30 (0.53) | TP53GPR119USP30TACR1 | |
| SCHEMBL2292408 | 0.90 | USP30 (0.53) | TP53GPR119USP30TACR1 | |
| SCHEMBL2273817 | 0.90 | USP30 (0.53) | TP53GPR119USP30TACR1 | |
| SCHEMBL2292403 | 0.90 | USP30 (0.53) | TP53GPR119USP30TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |