Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767115 | 0.86 | SLC6A4 (0.52) | EPHX2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL20767392 | 0.83 | CXCR3 (0.44) | SLC6A4SOS1OPRL1 | |
| SCHEMBL20766796 | 0.82 | SLC6A4 (0.46) | SLC6A4P2RX7SOS1SLC6A2SLC6A3 | |
| SCHEMBL8266958 | 0.82 | SLC6A4 (0.46) | EPHX2DDR1SLC6A4P2RX7SLC6A2 | |
| SCHEMBL20766457 | 0.81 | EPHX2 (0.62) | EPHX2SLC6A4P2RX7SLC6A2 | |
| SCHEMBL20766245 | 0.75 | HPGD (0.43) | SLC6A4SOS1SLC6A2OPRL1 | |
| Hydrochloric Acid SCHEMBL30924163 | 0.74 | EPHX2 (0.69) | EPHX2DDR1P2RX7 | |
| SCHEMBL8821375 | 0.73 | KMT2A (0.48) | SOS1 | |
| SCHEMBL20766503 | 0.71 | SLC6A4 (0.46) | SLC6A4SOS1SLC6A2SLC6A3OPRL1 | |
| SCHEMBL5992982 | 0.71 | BCHE (0.58) | EPHX2SLC6A4SLC6A2SLC6A3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672954-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | Acadia Pharmaceuticals Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019040107-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |