Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | IL1B | P01584 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766660 | 1.00 | DDB1 (0.64) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18270945 | 0.86 | DDB1 (0.65) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18270883 | 0.86 | DDB1 (0.63) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18263931 | 0.86 | DDB1 (0.63) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL3125601 | 0.85 | CRBN (0.55) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18263933 | 0.85 | CRBN (0.55) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19585360 | 0.85 | DDB1 (0.64) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19612069 | 0.85 | DDB1 (0.51) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19612072 | 0.85 | DDB1 (0.51) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL22845577 | 0.82 | DDB1 (0.67) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | BIOTHERYX, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. | 2020-07-23 | — | — | US | disclosed |
| EP-3672955-A1 | ETHER COMPOUNDS AND USES THEREOF | Biotheryx Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-111247138-A | Ether compound and use thereof | 拜欧赛里克斯公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019040274-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | EPCAM, ICAM1, SELE | DDB1 1001/4885CRBN 379/4885IKZF3 122/4885 |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | EPCAM, ICAM1, SELE | DDB1 1001/4885CRBN 379/4885IKZF3 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.