Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338742 | 0.89 | CETP (0.44) | CA1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL29172647 | 0.88 | CA1 (0.48) | CA1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL2799652 | 0.87 | CSNK1E (0.50) | TSHRALDH1A1MAPK1CETP | |
| SCHEMBL8086653 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL31548009 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL23857754 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL9684327 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL29121124 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL27945819 | 0.86 | CSNK1E (0.53) | MEN1KMT2AALDH1A1CETP | |
| SCHEMBL22369700 | 0.84 | CA1 (0.45) | CA1CYP2C19KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103146481-B | Method for preparing tobacco maillard reaction spice | HUABAO FOOD FLAVORS AND FRAGRANCES SHANGHAI CO LTD | 2014-05-28 | — | — | CN | claimed |
| CN-103146481-A | Method for preparing tobacco maillard reaction spice | HUABAO FOOD FLAVORS AND FRAGRANCES SHANGHAI CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-116368131-B | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-116368131-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116253724-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-13 | — | — | CN | disclosed |
| US-11312964-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210207146-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2021-07-08 | — | — | US | disclosed |
| CN-107175119-B | A kind of preparation method and applications of load-type vanadium phosphor oxide catalyst | 中国石油化工股份有限公司 | 2019-11-15 | — | — | CN | disclosed |
| EP-1833824-B1 | 3-CYCLOALKYLCARBONYL INDOLES AS CANNABINOID RECEPTOR LIGANDS | ABBVIE INC (US) | 2016-08-03 | — | — | EP | disclosed |
| CN-103146481-B | Method for preparing tobacco maillard reaction spice | HUABAO FOOD FLAVORS AND FRAGRANCES SHANGHAI CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-103146481-A | Method for preparing tobacco maillard reaction spice | HUABAO FOOD FLAVORS AND FRAGRANCES SHANGHAI CO LTD | 2013-06-12 | — | — | CN | disclosed |
| US-20110065685-A1 | NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-03-17 | — | — | US | disclosed |
| US-7750039-B2 | Indoles are cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2010-07-06 | — | — | US | disclosed |
| US-7560481-B2 | {1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(2,2,3,3-tetramethylcyclopropyl)methanone toluenesufonic acid salt; selectively target cannaboid B2 receptors; analgesics for both nociceptive and neuropathic pain; side effect reduction; immunology modulators; antiinflammatory agents; neuroprotectants | ABBOTT LABORATORIES (US) | 2009-07-14 | — | — | US | disclosed |
| US-20090149501-A1 | NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-06-11 | — | — | US | disclosed |
| EP-1833824-A1 | 3-CYCLOALKYLCARBONYL INDOLES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2007-09-19 | — | — | EP | disclosed |
| US-20070037801-A1 | {1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(2,2,3,3-tetramethylcyclopropyl)methanone toluenesufonic acid salt; selectively target cannaboid B2 receptors; analgesics for both nociceptive and neuropathic pain; side effect reduction; immunology modulators; antiinflammatory agents; neuroprotectants | ABBVIE INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2006069196-A1 | 3-CYCLOALKYLCARBONYL INDOLES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2006-06-29 | — | — | WO | disclosed |
| US-5242511-A | COPPER ALLOY COMPOSITIONS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149501-A1 | NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS | CNR2, CNR1, OPRL1 | CA1 2894/4885SLC1A3 1216/4885SLC1A2 624/4885 |
| US-20070037801-A1 | {1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(2,2,3,3-tetramethylcyclopropyl)methanone toluenesufonic acid salt; selectively target cannaboid B2 receptors; analgesics for both nociceptive and neuropathic pain; side effect reduction; immunology modulators; antiinflammatory agents; neuroprotectants | CNR2, CNR1, TRPV1 | CA1 3423/4885SLC1A3 2215/4885SLC1A2 1032/4885 |
| US-20110065685-A1 | NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS | CNR2, CNR1, OPRL1 | CA1 2894/4885SLC1A3 1216/4885SLC1A2 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.