Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31548009 | 1.00 | CSNK1E (0.53) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL23857754 | 1.00 | CSNK1E (0.53) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL29121124 | 1.00 | CSNK1E (0.53) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL8086653 | 1.00 | CSNK1E (0.53) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL9684327 | 1.00 | CSNK1E (0.53) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL2799652 | 0.98 | CSNK1E (0.50) | CSNK1ECETPCNR2CTRCALDH1A1 | |
| SCHEMBL3338742 | 0.93 | CETP (0.44) | CSNK1ECETPCNR2MEN1KMT2A | |
| SCHEMBL2076706 | 0.86 | CA1 (0.43) | CETPMEN1KMT2AALDH1A1 | |
| SCHEMBL6032859 | 0.84 | CSNK1E (0.50) | CSNK1ECETPCNR2CTRCMEN1 | |
| SCHEMBL6239894 | 0.84 | CSNK1E (0.50) | CSNK1ECETPCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450110-A | Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity and intermediate thereof | SHIONOGI & CO | 2013-12-18 | — | — | CN | disclosed |