Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767257 | 1.00 | GAA (0.38) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL27008084 | 1.00 | GAA (0.38) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL6120347 | 1.00 | GAA (0.38) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL27008132 | 1.00 | GAA (0.38) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL13711178 | 0.90 | GAA (0.45) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL14501404 | 0.86 | L3MBTL1 (0.40) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL23421691 | 0.85 | GAA (0.40) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL27173005 | 0.85 | BRD4 (0.35) | GAAPOLBSMN1; SMN2 | |
| SCHEMBL23421304 | 0.85 | GAA (0.40) | GAAALDH1A1MAPTTHRBATM | |
| SCHEMBL15227428 | 0.83 | HPGD (0.42) | GAAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |