Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 5/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095508 | 0.94 | PRKDC (0.45) | PRKDCERBB2RETPDGFRBKCNA3 | |
| Formamide SCHEMBL29160439 | 0.84 | PIK3CA (0.37) | PRKDCPIK3CDPIK3CBPIK3CG | |
| Formamide SCHEMBL29160413 | 0.78 | P2RY12 (0.39) | PRKDCKCNA3P2RY12LMNAL3MBTL1 | |
| SCHEMBL31035358 | 0.73 | P2RY12 (0.40) | PRKDCKCNA3P2RY12LMNAL3MBTL1 | |
| SCHEMBL28095893 | 0.72 | P2RY12 (0.44) | PRKDCKCNA3P2RY12PIK3CDPIK3CG | |
| SCHEMBL7329373 | 0.69 | P2RY12 (0.54) | PRKDCKCNA3P2RY12ALDH1A1KDM4E | |
| SCHEMBL31035311 | 0.69 | PRKDC (0.61) | PRKDCKCNA3P2RY12L3MBTL1ALDH1A1 | |
| SCHEMBL31035103 | 0.68 | NUDT1 (0.37) | PRKDCKCNA3P2RY12L3MBTL1MAPT | |
| SCHEMBL7319096 | 0.68 | PRKDC (0.54) | PRKDCRETLMNAPIK3CDPIK3CB | |
| SCHEMBL7315291 | 0.67 | PRKDC (0.59) | PRKDCP2RY12LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070166-A1 | Optimized Method for Treating and Curing Arthritis, Diabetes, Multiple Sclerosis and Other Autoimmune Disease | POSTREL RICHARD (US) | 2019-03-07 | — | — | US | claimed |
| CN-117615763-A | Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof | 健道生物医药有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-116096710-A | 4-oxo-3, 4-dihydroquinazolinone compounds for the treatment of BRAF related diseases and disorders | 阿雷生物药品公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114026073-A | Quinazolin-4-one derivatives for the treatment of BRAF related diseases and disorders | ARRAY生物制药公司 | 2022-02-08 | — | — | CN | disclosed |